You’ve probably seen David DeSandro‘s (@desandro) work many times, but perhaps you haven’t known it to be his. He’s kind of a magician. He’s one of those super creative intelligent guys always pushing the limits and making a whole bunch of people say “wow.”
I’ll go out on a limb and say that he’s probably most famous for jQuery Masonry, which is a layout plugin for jQuery. It’s quite nice, and it’s been used on more sites than I could count. His latest project is the successor(?) to Masonry, and it’s called Isotope. It’s definitely Masonry to the next level, and the screencast is a great illustration of how far it’s come.
Keep your eyes peeled, sounds like it’s being released quite soon.